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Sildenafil is effective for the treatment of ED, although 20–50% of patients who respond to sildenafil discontinue its use . Vardenafil has an average rating of 8. Viagra (sildenafil) is a brand-name prescription drug that’s used to treat erectile dysfunction (ED). Typically, it is recommended to take Sildenafil about 30 minutes to 1 hour before sexual activity. July 30, 2019. Other erectile dysfunction medications include tadalafil (generic for Cialis), avanafil , vardenafil and hard mints chewable ED meds. Cancel anytime subscriptions. Sildenafil is used to treat erectile dysfunction and pulmonary arterial hypertension. The inability to achieve and/or maintain an erection sufficient for satisfactory sexual intercourse is a distressing and common symptom, affecting up to one-third of adult men [ 1 ]. Whereas generic sildenafil is the generic version and is made by a number of manufacturers. 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