Ultrasound(pelvic and trans vaginal) that homogeneous endometrium is seen measuring 5 - 6 mm. What do these results mean: ENDOMETRIAL BIOPSY: WEAKLY PROLIFERATIVE ENDOMETRIUM. The mean endometrial thickness measured on each day of the proliferation curve correlated closely with the mean estradiol levels measured on that day (coefficient 0. ICD-10-CM Coding Rules. Be sure to rule out a neoplastic process (endometrial hyperplasia or carcinoma) Stromal metaplasias (while uncommon) include osseous, cartilaginous, myomatous, adipose and synovial-like. 6% in postmenopausal patients, 91% in premenopausal patients, and 81% for EIN. In this study we correlate the # of plasma cells by H&E to the # of plasma cells by CD138 IHC in endometrial biopsies. Early proliferative (day 4-7 ) Straight short glands, thin epithelium. Endometrial hyperplasia is a condition that causes abnormal uterine bleeding. This diagnosis means that after examining your tissue sample under the microscope, your pathologist saw irregular and dilated endometrial glands in the proliferative phase (growing phase). It is a physiological response seen in pregnancy. 6 kg/m 2; P<. 6 kg/m 2; P<. N85. Decidua and decidualization redirect to this article. Demosthenes, MD. The specimen is received in formalin and consists of fragments of soft tan hemorrhagic tissue with admixed mucus aggregating to 3. Proliferation is a noncancerous change in the endometrium. Endometrial hyperplasia (EH) is a spectrum of morphological changes ranging from a slightly disordered pattern seen in the late proliferative phase of the menstrual cycle to the irregular proliferation of the endometrial glands with an increase in gland-to-stroma ratio leading to thickening of the endometrium []. A nonneoplastic lesion of myometrial tissue characterized by the presence of endometrial glands and stroma within myometrium. 1 Definition and Clinical presentation . During the same period, there are concurrent changes in the endometrium, which is why the follicular phase is also known as the proliferative phase. 0001). Biopsy results may show cell changes linked to hormone levels, or abnormal tissues, such as fibroids or polyps. Hysteroscopy can identify malignant or benign pathology with approximately 20% false-positive results. Initial evaluation — The primary goal in the diagnostic evaluation of postmenopausal patients with uterine bleeding is to exclude malignancy since increasing age is a risk factor for endometrial carcinoma ( table 1 ). What does this mean? endometrium, biopsy: disordered proliferative endometrium with associated simple (cystic) hyperplasia. 0–3. Conclusion One in six postmenopausal women who underwent endometrial sampling had proliferative endometrium. Figure 1. Interestingly, presence of polyp tissue was associated with endometrial cancer outcome in both the unadjusted (univariate) and adjusted (multivariable) models (OR 4. Early age at marriage and early sterilization also play a role. DDx. A repeat "d&c after ablation " is usually not going to produce different results. There is, however, variation within the endometrial thickness depending on the vertical position of the tissue in relation to the surface epithelium and the endometrial–myometrial junction (Figure 14. Created for people with ongoing healthcare needs but benefits everyone. Indeed polyps, adenomyosis, and leiomyomas have all been associated with an increased likelihood of abnormal endometrial molecular expressions thought to impair implantation and early embryo development. Proliferative Endometrium in Menopause: To Treat or Not to Treat? Obstet Gynecol. Personal hx colorectal cancer Endometrial polyp Morbid obesity Presence of one or more factors, increases risk by 8 times. The significance of the findings is that the metaplasia may present an. At the start of the menstrual cycle, the ovaries secrete the estrogen hormone, triggering the endometrium to enter a proliferative phase, during which it. Definition and Classification. Hormonal imbalances: Hormonal imbalances, such as decreased levels of estrogen and progesterone, can contribute to the endometrium. The specimen is received. Ed Friedlander and 4 doctors agree. , from endogenous sources such as obesity or from. Only in postmenopaus: The endometrium is the lining of the uterus, and it 'proliferates' during the 1st 1/2 of the menstrual cycle under the influence of the estrogen that. Created for people with ongoing healthcare needs but benefits everyone. It is diagnosed by a pathologist on examination of endometrial tissue under a microscope. 00 may differ. Created for people with ongoing healthcare needs but benefits everyone. Disordered proliferative endometrium (DPE) and hyperplasia without atypia. Literature shows that a diagnosis of chronic endometritis is often possible when tissue samples are taken in the proliferative phase of the endometrium rather than the secretory phase. If left untreated, disordered proliferative endometrium can change into another non-cancerous condition called endometrial hyperplasia. This definition comprises various types of hormonally induced metaplastic changes in the endometrium observed both in benign and premalignant or malignant conditions [9,10,11]. Contexts. It is a normal finding in women of reproductive age. 9 vs 30. Absence of uterine bleeding. 8% of hysteroscopies and in 56. Female Genital Pathology. Contact your doctor if you experience: Menstrual bleeding that is heavier or longer-lasting than usual. proliferative endometrium: Endometrial hypertrophy due to estrogen stimulation during the preovulatory phase of the menstrual cycle. 09–7. Disordered proliferation of endometrium just means that you have hormonal imbalance. "Exodus" pattern is a term used to describe exfoliation of endometrial cells during the proliferative phase. The polyp is made up of an increased number of otherwise normal-appearing endometrial glands and stroma. No malignancy was recognized. that is what weakly proliferative endometrium means. General Surgeon. Physician. Endometrial hyperplasia without atypia (as in the 2020 WHO classification) is defined as the proliferation of endometrial glands of irregular size and shape without significant cytological atypia. It is also simply known as endometrial polyp which is a somewhat ambiguous descriptor as not all endometrial polyps are benign. Blood. It may be associated with abnormal menstrual bleeding or infertility. BIOPSY. Learn how we can help. • 01-2021 Vaginal Ultrasound: Showed 3 fibroids, endometrium lining 8. 9. For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk. The impact of the endometrial proliferative phase on human embryo implantation remains unclear, but deserves further attention, especially since in luteal phase endometrial biopsies, a transcriptional signature predictive for repeated implantation failure has been associated with reduced cell proliferation, possibly indicating proliferative. 2 percent) By comparison, the background prevalence of endometrial pathology in postmenopausal patients without bleeding is lower. Some, but not all features of atrophy may also be seen in women of fertile age. My pathology report final diagnosis are as follows: Endometrium biopsy: blood and weakly proliferative phase endometrium with glandular and stromal breakdown. The ratio of glands to stroma increases compared to the normal proliferative phase endometrium, exceeding the ratio of 3:1 in hyperplasia. There's been a Bank Holiday which usually delays issues. This is healthy reproductive cell activity. 00 became effective on October 1, 2023. Characteristics. We distinguished basalis endometrium from functionalis endometrium by defined histological criteria as described previously by Hendrickson et al. Pathology 51 years experience. No apparent endometrial hyperplasia was seen. Definition / general. Recognition as an Endometrial Stromal Neoplasm (Biopsy/Curettage Specimen) The first clue that a biopsy/curettage specimen harbors an endometrial stromal neoplasm is the finding of multiple. Endometrial metaplasias and changes (EMCs) are conditions frequently overlooked and misdiagnosed. 7% cases and weakly proliferative endometrium in 34. 186 satisfied customers. doi: 10. For example, the endometrium in most term foetuses and neonates is only weakly proliferative, despite prolonged exposure to very high concentrations of unbound estrogens and progesterone in utero. 8 may differ. What do these results mean: ENDOMETRIAL BIOPSY: WEAKLY PROLIFERATIVE ENDOMETRIUM WITH FOCAL STROMAL AND/OR GLANDULAR BREAKDOWN. It is also seen in exogenous estrogen therapy and is a result of dys-synchronous growth of the. 1646 postmenopausal women aged 55-96 (mean 64. A hysterectomy stops symptoms and eliminates cancer risk. After menstruation, proliferative changes occur during a period of tissue regeneration. However, in some instances, they cause pain, irregular bleeding, or infertility. ( I have had 5 endometrium biopsies over past 4 years and one D&C 6 years ago) • 01-2021 Endo Biopsy Diagnosis: Pre-hyperplasia, Disordered proliferative endometrium without atypia. 4 It is a disease of ageing, with over 80% of cases occurring during the. Objective In the last two decades, many reports demonstrated the unreliability of endometrial biopsy pathology showing an AH (atypical hyperplasia) to exclude a synchronous EEC (endometrioid endometrial carcinoma), with an underestimation of EEC in up to 50% of women. How is proliferative endometrium treated? Endometrial hyperplasia treatment The most. 2. Compact. Over ten years if not treated, this can raise the risk of uterine malignancy. In your case, there could be no enough progesterone to organize the proliferation caused by the estrogen and when the phase of secretion. ), 19% premalignant lesions, and. 0 x 3. At the start of the menstrual cycle, the ovaries secrete the estrogen hormone, triggering the endometrium to enter a proliferative phase, during. 3% had proliferative pattern (disorder type) tissue; 0. 100 endometrial biopsies were selected, excluding specimens with limited material, cancer and menstrual phase. The physiologic changes of the endometrium during reproductive life and after menopause reflect the influence of ovarian-secreted steroid sex hormones and of their withdrawal. Metaplasia is defined as a change of one cell type to another cell type. The endometrium becomes thicker leading up to ovulation to provide a suitable environment for a fertilized egg to grow inside the uterus. breakdown. - Negative for polyp, hyperplasia, atypia or. N85. Learn how we can help. Hormonal or irritative stimuli are the main inducing factors of EMCs, although some metaplasias have a mutational origin. 5% of women with abnormal uterine bleeding had proliferative or secretory endometrium. What does this mean? waiting to hear from doctor. "FRAGMENTS OF WEAKLY PROLIFERATIVE ENDOMETRIUMWITH GLANDULAR AND STROMALBREAKDOWN"? Can somebody explain this to me in English please? Answer. Proliferative endometrium is a very common non-cancerous change that develops in the tissue lining the inside of the uterus. 4 It is a disease of ageing, with over 80% of cases occurring during the. Adenomyosis is a benign uterine disorder in which endometrial glands are found in the myometrium of the uterus. A Verified Doctor answered. The Proliferative Phase. In proliferative endometrium, the level of expression was increased, but still much less than those seen in the malignant epithelial cells. "My gynecologist did the biopsy to rule out uterine cancer (which neither of us thought I had), as we try to determine the cause of my dysfunctional uterine bleeding. X. Biopsy was done because I had a day of spotting 17 months. Endometrium with changes due to exogenous hormones is relatively common in endometrial samples. 0000000000005054. Estrogen only: weakly to markedly proliferative endometrium, stromal breakdown, squamous morules Progestogen only: scant. Definition focal overgrowth of localized benign endometrial tissue. Adenofibroma is a mixed tumor of the endometrium (and rarely also of the cervix) consisting of a benign epithelial and a benign mesenchymal component, both of which are integral components of the neoplasm. Among those women, 278 had a proliferative endometrium, and 684 had an atrophic endometrium. It can be acute (starts suddenly and is short-term) or chronic (lasts a long time or occurs repeatedly). 09–7. The endometrium is a complex tissue that cyclically regenerates every menstrual cycle in preparation for embryo implantation. Disordered proliferative endometrium with glandular and. It is also the early proliferative phase and hence, a mixture of changes associated with menses and the early proliferative endometrium is seen . The Proliferative Phase. X. 2 vs 64. Doctor of Medicine. Definition/Introduction. 10170. FRAGMENTS OF BENIGN ENDOCERVICALTISSUE. Learn how we can help. At the end of this stage, around the 14th day, the. 0% had weakly proliferative endometrial histology, 0. Endometrial morphology after 6 months of continuous treatment with a new gonadotropin-releasing hormone superagonist for contraception. 2023 Feb 1;141 (2):265-267. 8% of all surgical specimens of women with PE. Prognosis. The proliferative phase is the variable part of the cycle. Pseudoneoplastic glandular response of the female genital tract, first described by Javier Arias-Stella in 1954 as atypical endometrial changes associated with the presence of chorionic tissue ( AMA Arch Pathol 1954;58:112 ) Typically found in the endometria of postabortion curettings of intrauterine or extrauterine pregnancies or with. Endometrial polyps are benign in nature and affect both reproductive age and postmenopausal women. Hysteroscopy is the gold standard to evaluate the endometrial cavity. It is a normal finding in women of reproductive age. This refers to: Build up of the uterine lining, as would happen in the cycle prior to ovulation (egg release) to prepare for implantation of the fertilized egg. 9 vs 30. Pathology report states: postmenapausal weakly-proliferative endometrium with focal glandular crowding. The spectrum of. About 3. Risk factors for developing endometrial cancer after benign sampling Factors independently associated with subsequent endometrial cancer. Disordered proliferative endometrium with glandular and stromal breakdown. Harold Fields answered. An endometrial polyp is a usually noncancerous growth attached to the inner wall of the uterus, common for women undergoing or who have completed menopause. DDx. Because atrophic postmenopausal endometrium is no longer active, there are few or no mitotic cells. Proliferative endometrium refers to the time during the menstrual cycle when a layer of cells is being prepared for a fertilized egg to attach to. No worries, I know what you mean for sure. I. Proliferative endometrium describes the 'stage' of the endometrium when it was biopsied. Note that when research or. Other nonendometrioid subtypes seen in. Read More. I'm 51, no period 8 months, spotting almost every day for year. My endometrial biopsy says "small fragments of weakly proliferative type endometrum admixed with abundant mucus" I am currently on an OCP. At the same time, menopausal endometrium is. A proliferative endometrium in itself is not worrisome. Hormonal or irritative stimuli are the main inducing factors of EMCs, although some metaplasias have a mutational origin. Endometrial polyps. SEE COMMENT. Many people find relief through progestin hormone treatments. The mean follow. Clin. See also: endometriumPMID: 12611094. ( I have had 5 endometrium biopsies over past 4 years and one D&C 6 years ago) • 01-2021 Endo Biopsy Diagnosis: Pre-hyperplasia, Disordered proliferative endometrium without atypia. 8% of all surgical specimens of women with PE. People who have atypical endometrial hyperplasia have a higher risk of developing uterine cancer. The code is valid during the current fiscal year for the submission of HIPAA-covered transactions from October 01, 2023 through September 30, 2024. Endometrial cancer begins in the layer of cells that form the lining of the uterus, called the endometrium. However, in some instances, they cause pain, irregular bleeding, or infertility. 9 and 12. Between the 19th and 23rd day of a typical 28-day cycle (the mid-secretory phase), the degree of glandular secretion increases. A hysterectomy makes it impossible for you to become pregnant in the future. This pattern may be seen in the perimenopausal years, or in postmenopausal years if there is a source of at least low-level estrogenic stimulation (e. It is further classified. read more. It has a basal layer and a functional layer: the basal layer contains stem cells which regenerate the functional layer. K. This pictorial review takes you through the hysteroscopic view of normal-looking. To understand it fully, estrogen and progesterone are the 2 hormones that makes this proliferation in order. Endometrial Stromal Nodule (ESN) and Low-Grade Endometrial Stromal Sarcoma (LG-ESS) ESN is a benign, whereas LG-ESS is a malignant neoplasm of the uterus (affecting the body of the uterus more than the cervix) and extra-uterine sites [8,9]. Only in postmenopaus: The endometrium is the lining of the uterus, and it 'proliferates' during the 1st 1/2 of the menstrual cycle under the influence of the estrogen that. Cancer can affect the uterus, the hollow, pear-shaped organ where a baby grows. The immunohistochemical staining pattern for CD138 with appr. The specimen is received. I am postmenopausal with uterine bleeding. The study of endometrial carcinoma at menopause presents an interesting challenge. Endometrial hyperplasia is a condition of the female reproductive system. The aim of this review is to update current issues and provide a classification with a practical clinicopathological approach. 7% cases and weakly proliferative endometrium in 34. Endometrial carcinoma is the most common invasive neoplasm of the female reproductive tract. Endometrial Polyp - Fragments of weakly proliferative/ inactive endometrium. The mean BMI of the cohort was 34. stroma. Proliferative is first part of cycle, dominated by estrogen. Your healthcare provider may suggest an endometrial biopsy if you have: Abnormal menstrual bleeding. Screening for endocervical or endometrial cancer. 0% Weakly Proliferative Endometrium 129 12. The immunohistochemical staining pattern for CD138 with appropriate controls supports the above diagnosis. Dr R. 5 years; P<. 0001) and had a higher body mass index (33. 81, p < 0. Most endometrial carcinomas maintain endometrioid differentiation; these also can contain areas of mucinous or squamous differentiation. New blood vessels develop and the endometrial glands become bigger in size. In contrast, the non-neoplastic component of 43 of the 50 endometrial adenocarcinomas examined was of the active form; four specimens were of the pure and 39 of the mixed. I'm sure your physician is monitoring your endometrial lining via biopsy or D&C to make sure that you aren't at increased risk of endometrial hyperplasia or pre-cancer of the endometrium. Conditions that involve the endometrium and may impact fertility include: Adenomyosis. Fewer than 2% of cases of endometrial hyperplasia without cytological atypia progress to endometrial carcinoma, compared with 23% of cases of endometrial hyperplasia with cytological atypia that progress to carcinoma (atypical hyperplasia; Kurman et al. Results: After intervention in letrozole group, response to treatment was seen in 93% cases (including endometrial atrophy in 58. Represents the most common form and is characterized by glandular proliferation, with variable shape and size, bordered by proliferative epithelium with mitotic activity; the interglandular stroma can be reduced, the differentiation from endometrial hyperplasia being made on account of the vessels with. Hysteroscopy combined with biopsy increases the accuracy of diagnosis up to 100%. 09–7. 1. Some, but not all features of atrophy may also be seen in. Created for people with ongoing healthcare needs but benefits everyone. This is essentially a normal report for your age. 3 Metaplasia in the endometrium can occur in both the epithelium and rarely the stroma. 2 percent) Hyperplasia without atypia (2 percent) Hyperplasia with atypia (0. Doctor's Assistant: Anything else in your medical history you think the doctor should know?Metaplasia is defined as a change of one cell type to another cell type. They described functional endometrium as being “weakly proliferative” or “weakly. Endocervical/tissue: A "pap smear" may contain some tissue from the canal leading to the womb (endocervical canal) which grows out over the surface of the cervix and is se. Not having a period (pre-menopause)The degree of proliferative activity can usually be assessed by the mitotic activity in both the glandular epithelium and the stroma. 5 years; P<. A slightly disordered endometrium is a form of cancer. 3–10% of endometrial biopsies are said to show histologic evidence of chronic endometritis. It aims to clarify the diagnostic criteria and differential diagnosis of these lesions, as well as their possible association with endometrioid neoplasia. 2 vs 64. SEE COMMENT. Re: Disordered Proliferative Endometrium. Hysteroscopy is now considered the standard diagnostic tool. More African American women had a proliferative. Treatment also usually includes the removal of the fallopian tubes and ovaries, called a salpingo-oophorectomy. What do these results mean: ENDOMETRIAL BIOPSY: WEAKLY PROLIFERATIVE ENDOMETRIUM WITH FOCAL STROMAL AND/OR GLANDULAR BREAKDOWN. Furthermore, 962 women met the inclusion criteria. Endometrial stromal tumors (ESTs) are rare mesenchymal tumors occurring primarily in the uterine corpus. No malignancy was recognized. 8 became effective on October 1, 2023. endometrium, biopsy: - consistent with menstrual phase endometrium: -- weakly proliferative endometrial glands with neutrophils and apoptosis. 5 ±17. 5. What is it? Symptoms Complications Treatment Summary Disordered proliferative endometrium can cause spotting between periods. Diagnosis: Fragments of weakly proliferative/inactive endometrium. The endometrium becomes thicker leading up to ovulation to provide a suitable environment for a fertilized egg to grow inside the uterus. 5 cm. An “insufficient” EMB result should always be viewed cautiously, especially in the setting of persistent postmenopausal bleeding. Introduction. Very heavy periods. Posts: 864. . Frequent, unpredictable periods whose lengths and heaviness vary. Endometrial biopsy showed a weakly proliferative Endometrium. Glandular tissue usually inactive and of basalis or proliferative type endometrium, but one fourth is functional; hemosiderin is generally absent (Am J Obstet Gynecol 1971;110:275)Endometrial hyperplasia (EH) is categorized into two groups: EH without atypia and EH with atypia (also referred to as endometrial intraepithelial neoplasia [EIN]). Proliferative endometrium indicates the follicular phase; whereas, secretory endometrium indicates luteal phase. Baisal. Blood. Women with a proliferative endometrium were younger (61. MD. Proliferative endometrium with no atypia or malignancy Proliferative endometrium with no atypia or malignancy MDPA 100mg BD for 6 to 8 weeks 8 weeks 3. Proliferative endometrium(15%) and secretory endometrium (5%) were identified in the postmenopausal women which is a comparable finding to other studies that reported a proliferative endometrium. 3. In this phase it is called Proliferative Endometrium. The asymptomatic disease free postmenopausal endometria derived from the prolapsed uteruses were atrophic and inactive in 42 of the 84 women, atrophic and weakly proliferative in 22, and of mixed form in 20 women. 5. Microscopic findings. A repeat "d&c after ablation " is usually not going to produce different results. Normal proliferative endometrium contains glands that are regularly spaced and that lie within stroma at a gland: stroma ratio of 1 to 1. 1097/AOG. Looking for help on a biospy report : weakly proliferative endometrium with progestin effect description is Fixative:Formalin NO. Weakly proliferative endometrium does not denote a specific functional state but is better conceptualized as a morphologic pattern. Can be pedunculated or sessile, single or multiple, and up to many centimeters in size. During menopause, the ovaries produce fewer hormones, leading to a cessation of the menstrual cycle. [10]: (1) constant appearance of basalis throughout the menstrual cycle, (2) glands of the basalis appear weakly proliferative, (3) basalis cells lack secretory features and the stroma is spindled. « lining in uterus thickened | Cells from uterus that show up in a pap ». This study examines the morphological and immunohistochemical features of endometrial metaplastic/reactive changes that coexist with endometrial hyperplasia and carcinoma. Van den Bosch et al 11 found that 14. Women with a proliferative endometrium were younger (61. Surgery. However, adenomyosis can cause: Heavy or prolonged menstrual bleeding. The risk. 3,245 satisfied customers. . What layer of the endometrium is shed during the. EH, especially EH with atypia, is of clinical significance because it may progress to. For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts. This pictorial review takes you through the hysteroscopic view of normal-looking. 4. Read More. . The belief that stromal cell proliferations in the endometrium are by definition neoplastic was first challenged by Stewart et al. What does this mean?Endometrial biopsy:benign proliferative endometrium with ciliated cell metaplasia without hyperplasia or malignancy. In the present pictorial review, we briefly discuss the various morphologic. Plasma cells were rare in inactive endometrium and noted in only 18% of unremarkable proliferative endometrium, all grade 1. Normal : It's benign tissue that shows estrogen effect (proliferative endometrium), cell changes that are benign (ciliated metaplasia) & no precancerous or can. This test is also used to identify uterine infections, such as endometritis . Menstrual endometrium is characterized by an influx of inflammatory cells, thrombi in stromal vessels, apoptosis and gland-stromal dissociation. Exogenous hormones taken for various reasons may have an effect on the morphology of endometrium, endometrial stroma and myometrial lesions, such as leiomyomas. Keywords: endometrium, atrophic, inactive, weakly proliferative, endometrial adenocarcinoma. Physician. Fibrosis of uterus NOS. Among those women, 278 had a proliferative endometrium, and 684 had an atrophic endometrium. Endometrial hyperplasia (EH) is a pre-cancerous, non-physiological, non-invasive proliferation of the endometrium that results in increased volume of endometrial tissue with alterations of glandular architecture (shape and size) and endometrial gland to stroma ratio of greater than 1:1 [5,6]. 02 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. Endometriosis can reactivate after menopause, particularly if estrogen levels rise again, such as after starting hormone replacement therapy. Early detection and accurate diagnosis of these lesions and its precursor by endometrial cytology is now accepted in Japan and regarded as an effective primary method of evaluating endometrial pathology (atypical hyperplasia or carcinoma). The endometrium repairs itself and it becomes thicker. Pediatrics 35 years experience. Weakly proliferative endometrium is a normal finding in some women, but it can also be a sign of cancer or other problems. For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk. The risk. Endometrial biopsy was performed 3 to 4 weeks after completion of therapy to assess response. In one study, follow-up outcomes of "gland-crowding" reports show 77% benign lesions (proliferative endometrium, secretory endometrium, endometrial polyp, etc. A member asked:. Conclusions: At least half of the disease free postmenopausal atrophic endometria show a weak proliferative pattern, either diffuse or focal, probably as a response to continuous. The pathologist must be aware of the spectrum of endometrial metaplasias encountered and the clinical setting in which they. The menopausal status as well as the date of onset of the last menstrual period and the length of the menstrual cycle in premenopausal women should be provided. Currently, the incidence of EH is indistinctly reported. I've recently had hysterscopy done and this is my. Definition and Classification. Ultrasound Results mild endometrial thickening 7-8 mm. benign. Endometrial ciliated and tubal metaplasia Ciliation is a characteristic feature of Müllerian epithelia, and its ubiquitous presence in the cervix, isthmus and normal proliferative endometrium could suggest that lesions exhibiting a predominant ciliated component do not represent a true metaplasia but rather a hyperplasia of ciliated cells.